Job Description

Job Description

We are searching for a Lead Principal Investigator to oversee a fast-growing clinical research site in San Francisco. This is a critical leadership role with direct impact on sponsor confidence, patient recruitment, and continuity of studies across a diverse therapeutic portfolio.

In this role, you will:

• Provide medical leadership across a broad range of studies.
• Serve as Principal Investigator on multiple trials.
• Oversee and mentor a team of Principal and Sub-Investigators.
• Build trust with patients, sponsors, and regulatory bodies through credibility and leadership.
• Help drive the growth and expansion of a high-demand clinical research site.

The Ideal Profile

• MD/DO (additional therapeutic range strongly preferred).
• 5+ years of direct patient care experience.
• 2+ years of hands-on clinical research experience as a PI.
• Demonstrated ability to attract patients or sponsors through strong reputation and track record.
• Collaborative leadership style with the ability to guide investigators and clinical staff.

Compensation & Benefits

• Competitive salary based on experience.
• 20% annual bonus linked to site revenue and performance goals.
• Relocation sign-on bonus available for non-local candidates.
• Strategic influence within a high-growth, well-respected research environment.

Why This Role?

This opportunity is ideal for a senior physician who wants to:

• Oversee a diverse therapeutic portfolio.
• Join a fast-growing site with strong sponsor demand and significant year-over-year revenue growth.
• Shape the future of a clinical research team positioned for long-term success.

Next Steps

If you meet the requirements and are open to exploring this opportunity, please apply confidentially for a discreet discussion.

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